Nolvadex that is often shortly called Nolva is the oldest and most popular brand name for the active substance Tamoxifen (or its full name Tamoxifen Citrate). This is also one of the oldest and most widely used SERMs on the market. Regardless if talking about bodybuilding purposes or medical purposes.
- PS: If you’re searching for Nolvadex during the cycle for a medical condition, we highly recommend you to talk with a doctor.
Nolvadex (Tamoxifen Citrate) is a drug classified as an Anti Estrogen – these are medications that are helping to reduce the level of estrogens in the body.
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How Does Nolvadex Work?
- SERMs (Selective Estrogen Receptor Modulators) like Nolvadex (Tamoxifen Citrate) or Clomid (Clomiphene Citrate) are only blocking the estrogen activity in specific parts of the body.
- Aromatase Inhibitors (AIs) which are also Anti Estrogens are actually lowering the estrogen amount in the body. SERMs do not lower estrogen in circulation.
SERMs are not blocking the aromatase enzymes from converting into estrogen. They are just binding to the estrogen receptors and taking their place. Hence they prevent the hormone from binding.
But Nolvadex (Tamoxifen), exactly as all other SERMs, are working in different ways in different parts of the body. In breast tissues, it blocks estrogen activity. But in the liver or ovaries, it boosts estrogen activity.
That’s why Nolvadex is helpful for treating estrogen receptor positive (ER+) breast cancer in women. But is helpful to treat gynecomastia in men. Plus is helpful for ovulation induction in women.
Because of the way it works, Tamoxifen Citrate is widely used for treating or preventing gynecomastia during the use of aromatized steroids. Or it also can be used to boost testosterone levels after their natural production was suppressed due to the use of steroids.
That’s why Nolvadex can be used for PCT.
Or use Nolvadex during the cycle for gynecomastia related issues.
Benefits of Nolvadex During Cycle
As it was earlier mentioned, Tamoxifen is an anti estrogen, but it doesn’t lower estrogen levels. It blocks estrogen activity in specific parts of the body. That’s why Tamoxifen is not very popular during the use of steroids (during the cycle) because it can’t help dealing with all estrogen related side effects. It only helps with some of them. Aromatase Inhibitors (AIs) can deal with all estrogen related issues, so they are more preferred.
Nolvadex is mostly seen as PCT medication, yet is still used during the cycle of steroids.
Nolvadex (Tamoxifen Citrate) is blocking the receptors in breast tissues. That’s how it prevents the estrogen from causing gynecomastia. Or dealing with existing gynecomastia symptoms.
So is helpful during the use of aromatized steroids. Specifically aromatized steroids, because those that do not convert into estrogen, won’t cause high estrogen. Therefore, no gyno.
Is important to remember that the enlargement of breast tissue can be permanent in case it is not going to be treated immediately and properly. Tamoxifen is known as one of the most powerful compounds that can deal with this condition, that’s why Nolvadex during a cycle is so effective for this purpose.
Gynecomastia in men is mostly caused by the spike of estrogen levels and Nolvadex is known to block the receptors of estrogen in the breast tissues. So is great to prevent it, but as mentioned, is not capable of dealing with bloating, raised blood pressure, and others. That’s because they are occurring from estrogen increase in blood serum levels and Tamoxifen has no effect on it.
In the end, Nolvadex during the cycle is used to prevent gynecomastia. But is mostly used as a part of the PCT plan. Because of estrogen blocking effects on the pituitary gland, the compound helps boost natural testosterone production.
Nolvadex During Cycle Dosage
- If Nolvadex is used for PCT plans, then it usually is started at higher doses like 40 mg per day (2 tablets) for about 2 weeks. Then the dosage is decreased to 20 mg per day for 2 more weeks (total 4 weeks).
Dosages can be adjusted according to personal responses to as low as 10 mg per day.
- Nolvadex during cycle dosage can be slightly higher. Is almost never used in doses lower than 20 mg per day. But can be used in doses as high as 80 mg per day.
In case it is used as prevention of gynecomastia symptoms then the dosage is usually the lowest possible. Then increased only if needed.
In case it is used as a treatment of gynecomastia symptoms then is usually started at higher doses (like 40, 60, or even 80 mg per day). Then the dosage is reduced as symptoms go away. Is used for the entire steroids cycle length.
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