Letrozole (popular name Femara among others) is a non suicidal Aromatase Inhibitor (AI) that comes as an oral pill. According to both studies and people who experimented with it – this is the most potent Aromatase Inhibitor out there. Letrozole is one of the three most popular and commonly used AIs by steroid users for controlling the side effects associated with high estrogen levels as a result of using aromatizing steroids. Those steroids that convert into estrogen through the process of aromatization (binding to aromatase enzymes). Letrozole is binding to those aromatase enzymes not allowing steroids to do so, thus, lowering estrogen. Therefore, it protects from high estrogenic symptoms and steroids side effects.
The other two common Aromatase Inhibitors (AIs) are Arimidex (Anastrozole) and Aromasin (Exemestane).
But since Letrozole is so powerful at reducing estrogen levels, it’s often seen as a last resort drug. That’s why it is perhaps the least popular out of the three AIs. Being so powerful, users are likely to suppress estrogen levels too much. Therefore, they only keep it as a drug that is going to be helpful in lowering estrogen in case the other two fail.
- Generally, I have to mention that there’s literally nothing else better that could help you deal with gynecomastia. Letrozole is the best anti-gynecomastia drug in existence. But it is also helpful in lowering the risks of other high estrogen symptoms too. Such as water retention, high blood pressure, and others.
In the end, as any other AI, Letrozole (Femara) is appealing to users of aromatizing anabolic steroids like Testosterone, Dianabol (Methandienone), Nandrolone (Deca or NPP), Equipoise (Boldenone), and others.
What is Letrozole (Femara)?
Exactly like all other Aromatase Inhibitors that people use for protection against the high estrogenic side effects of anabolic steroids, Letrozole is a drug that was developed and is still approved by the FDA for treating hormonally positive breast cancer in women.
This is a drug that lowers estrogen. And in case the cancer is caused by estrogen, Letrozole can be highly effective for treating breast cancer in women. But there are other uses as well when the patient may need to lower estrogen levels.
But the most important thing that you should be aware of is that Letrozole (Femara) is able to lower the overall estrogen levels as a result of blocking aromatase enzymes. And it has the most powerful estrogen reducing effects.
Although SERMs are also anti-estrogens, they are very different from Aromatase Inhibitors (AIs). They don’t lower estrogen levels, they block the estrogen receptors in specific parts of the body.
That’s why Letrozole is helpful at mitigating water retention, high blood pressure that comes along with the excess of water retention, and other high estrogen symptoms. Nonetheless, the most popular use of Letrozole is to deal with gynecomastia (man’s boobs).
Letrozole Side Effects
So, you know that Letrozole is doing a great job in protecting and controlling (lowering) high estrogen symptoms. This is a drug that you should have handy in case you’re thinking of introducing anabolic steroids to your regimen (those that aromatize into estrogen). That’s because this way you can use it whenever you notice high estrogen symptoms and get the protection.
Nonetheless, never underestimate Letrozole side effects. By administering too high a Letrozole dosage, this drug is going to reduce too much estrogen levels. While you may think that estrogen is a female hormone so there’s no need for it – you’re making a huge mistake.
- Lowering estrogen levels too much (as a result of using too high a dosage and/or using it for too long and suppressing estrogen for too long) is going to lead to many side effects. Estrogen is an important hormone for females, but it’s very important for men too.
For example, estrogen helps you grow muscles and gain strength. Without this hormone, you may notice strength loss and an inability to grow muscles. It’s also a hormone that affects your central nervous system. Without estrogen, you may suffer chronic fatigue, insomnia, and many other issues.
Estrogen is also important to maintain proper cholesterol health. Steroids are already affecting cholesterol in a negative way, suppressing estrogen too much is likely to cause too many negative effects on cholesterol.
Another Letrozole side effect is bone and/or joint pain. That’s because the estrogen hormone is important for bone mineralization and overall bone health. Too high estrogen reduction is likely to cause such issues. Is very important to keep the proper dosage in order to avoid the side effects of Letrozole – Femara.
Letrozole Dosage
Femara (Letrozole) is very powerful so you need to be very careful with it. It comes in the form of oral pills. I recommend using low doses because it’s likely to cause powerful estrogen reduction effects even at low doses.
I recommend using one dosage and waiting a few days and checking the results you’re experiencing before taking another one. Do not attempt to use it too often. Some people may need to use it only once a week, others may find the need to use it even less frequently. Yes, there are cases when some people may need to use it on a daily or every other day basis, but obviously, this increases the risk of suppressing estrogen levels too much.
It’s very important to maintain a sensible dose. Find what’s your best dosage because it varies from one person to another depending on a lot of factors such as steroids dosage, steroids number, cycle length, your personal response, and liability to convert into estrogen, and so on and so forth.
Dosages of about 0.5-1.25 mg every two days are enough to offer perfect estrogenic protection for most men. Only in case you notice some signs of gynecomastia, you could up the dosage to 2.5 mg every other day or even daily but that’s very rarely needed.
Conclusion
Letrozole is the most powerful aromatase inhibitor so you need to be very careful with it. You need to use it to control estrogen. The point of using Letrozole (Femara) is to keep estrogen within the normal range. Getting estrogen too low or too high is causing side effects. So, you have to find your perfect Letrozole dosage specifically for you and your needs.
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