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Letrozole VS Arimidex

Letrozole and Arimidex are very similar drugs and that’s why they are so widely compared to each other. Both are non steroidal aromatase inhibitors (AIs) and they are both highly favored by anabolic steroid users to prevent estrogenic side effects during the use of aromatizable steroids.

In fact, we need to compare Letrozole vs Anastrozole or Femara vs Arimidex taken in consideration that Letrozole and Anastrozole are the actual substances found in the brands Femara and Arimidex. You might find Letrozole and Anastrozole being sold as other brands, but Femara and Arimidex are the most popular brands for these substances.

Mono Femara by Beligas Arimidex by Beligas




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  • Since both are Aromatase Inhibitors (AIs), they are both working in similar ways, offering similar results and both having a similar side effect risk profile as well. Nonetheless, they are still 2 different products and that’s why someone might find one to be better than the other.

When comparing Letrozole vs Arimidex, it seems like Arimidex (Anastrozole) is generally taking the lead as being more popular and widely used among bodybuilders, but it doesn’t mean that it is better overall than Letrozole (Femara).

One of the factors that makes Arimidex more popular is due to availability and most importantly cost because this compound is considered cheaper compared to Letrozole.

Letrozole VS Arimidex For PCT

Both Letrozole and Arimidex are AIs that can help men to stimulate their natural testosterone production, nonetheless, they are both considered weak testosterone boosters and that’s why both are rarely used for such needs and neither is used as a PCT product alone even if used.

Yet, they are not as popular as Selective Estrogen Receptor Modulators (SERMs) like Nolvadex (Tamoxifen) or Clomid (Clomiphene) for Post Cycle Therapy purposes.

The main reason for that is because Arimidex is way too powerful for inhibiting estrogen and Letrozole is even more powerful, that’s why it could lead to too low estrogen levels in a male body.

In retrospect, Clomid and/ or Nolvadex is not going to suppress estrogen that much and would do a better job in boosting natural testosterone production.


Letrozole vs Arimidex Differences

There are a lot of similarities between these 2 compounds such as both being orally active aromatase inhibitors (AIs) that are not considered suicidal AIs and this means that none of them would permanently disable the aromatase enzyme (like Aromasin – Exemestane would).

Nonetheless, Letrozole (Femara) is still considered a much more powerful compound at inhibiting the estrogen levels compared to Arimidex (Anastrozole) even including Aromasin (Exemestane). In fact, it is considered much more powerful than the other two products for estrogen suppression.

But since Letrozole is so powerful, it is used by many as an emergency compound when estrogens are getting too high too fast. Since Arimidex is not as powerful, the side effects are not as harsh when we are comparing them to Letrozole, despite both offering similar side effects.

That’s because Letrozole is suppressing too much estrogen and despite estrogen being considered a female hormone, is still very important for a man. Without estrogen a man can suffer from erectile dysfunction, cannot gain muscles and strength so easily etc.


Arimidex is milder than Letrozole which is one of the most powerful AI you can use that can kill your entire estrogen. That’s why it is very powerful, but you need to be very careful.

  • If you need a really fast and huge suppression of estrogen, Letrozole is better.
  • If you need balanced estrogen suppression and a mild AI then Arimidex is better.

In the end, both are very effective compounds for dealing with estrogen related issues during the anabolic steroid cycle. That’s why we recommend having at least some AI handy when starting an aromatizable anabolic steroid cycle.


In the end, we cannot say which one is better than the other when comparing Letrozole vs Arimidex. There is not a right or wrong answer, it all depends on the steroid cycle that the user is planning to run, on personal tolerance, ultimate goals etc.

If we talk about which one is better in terms of estrogenic suppression then Letrozole is definitely a winner. But if we are talking about which one is milder in suppressing estrogen and therefore safer in side effects then Arimidex is a winner.

Arimidex 1mg Alpha Wolf Lab

femara 2.5 Alpha Wolf Lab



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Buy Letrozole Here



Some users benefit more from running Arimidex (Anastrozole) but others would find Femara (Letrozole) better for their needs.

In the end, although Arimidex is cheaper overall than Letrozole – we’re offering best prices for both these Aromatase Inhibitors sold here from You can be sure that both compounds are of best quality and cheapest price on the market.

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